Alongside Alzheimer’s disease, a lower hippocampal volume has been observed in people with many other conditions – such as Cushing’s disease, depression, PTSD and anxiety.Certain lifestyle habits can also worsen loss of hippocampus volume. For example, poor diet has been linked to a lower hippocampus volume, as has excess alcohol consumption – even in young people.
On the other hand, physical activity, including yoga, cardio and exercises which build balance and coordination, have all been shown to increase hippocampal volume in older people.
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Size of brain area linked with cognitive decline – even in people with no other warning signs of Alzheimer’s disease
This study shows at least two different mechanisms lead to cognitive decline – both in healthy people and people with Alzheimer’s.The Conversation